Evita - when she's dying
The Elephant Man - the end - and it being his choice
Carrie - there was never really any other outcome for her
Gone With The Wind - the end of part 1 (not only do I feel her sense of utter rock-bottom loss and new resolve, but it is realised in perhaps the most effectively 'epic' dramatic way of all on-screen time)
The Wizard Of Oz - Over the Rainbow (everything about the tragedy of Garland's life is just so tied up in her image there on the screen at that moment)