I put a s set of them on my frineds MV. As long as you clean the when really well. then rub it down with alchol to get the cleaning stuff off and be very patient it's pretty easy. I highly recommend taking the wheels off to do it.
If you were thinking of actually painting them on I would put the bike on it's side stand or support the from wheel. Then find a way to attach the paint pen to a fixed object and then just simply slowly and steadily spin the wheels. But the stickers have held up very well for him so far.