I can't speak for history, thankfully I'm not that old yet, however, in my lifetime, Wade Boggs and Tony Gwynn were tough to get out with being able to pencil in a "K" on your scorecard.
I don't know many players that were hard to strike out...not saying that there aren't any, all I can say is that when David Ekstein played for St. Louis in 2006 he swung and missed a total of seven times the whole season.