I can't agree with Mr. Smartypants enough - your first bike you are going to beat the heck out of, no matter how conservatively you ride it. When you take the fairings off for the first time and accidently (but also predictablely) strip the bolts, your heart is going to break, let alone anything mechanical. Get a used bike cheap to start, it'll probably last you a couple years at least before you run into mechanical problems, that if you are patient, you can probably fix yourself and will be a more knowledgable rider for it. Honda engines generally speaking do last a long time, I trust them.
The 250R has SOME balls, I'll give it that much, but you'll be bored of it's power limits within a year at the most. Look at 500-600cc 4 cylinder engines, those bikes will keep you entertained far longer. Searching on ebay with those search-criteria (engine size, year, cost) will help educate you on what the going rate for a decent starter bike of that size is. Just keep searching every day like you are window shopping, and don't buy anything on impulse. chances are you'll regret it,