I don't really see any similarities between Doyle Cleverlobe and Fry, other than them both being fish out of water (and that's not even a unique trait shared by them both since the main girl of the show, Aimee Brighttower, was likewise displaced from Earth).
Personality-wise, Doyle was a bit more like Reggie Mantle or Flash Thompson, a overconfident jock jerk. He was Big Man On Campus back on Earth and he expected to carry the same clout in Galaxy High, but he spent the rest of the series getting shot down, whereas Aimee, who was the shy wallflower/bookworm on Earth, became the popular girl in Galaxy High.
But yeah, I remember Galaxy High. It was a cool, quirky show. My favorite characters were probably the Bonk Bunch; generally I don't like cartoon bully characters, but Beef Bonk, Earl Ecch and Rotten Roland had a certain wackiness to them that made you like them despite what punks they were. (Earl Ecch was a lot like me as a teenager; beligerent and always paranoid about being stepped on.)
Galaxy High was a favorite show of my mom's; when it ran on CBS on Saturday mornings, she'd get up and watch it with us. Her favorite character was always The Creep; she loved his singing. :anime: