yes, you will have to bridge your subwoofers, but you have to be careful of power handeling because all the power is distributed evenly to the subwoofers
So make sure that you arent maxing ANY of the subwoofers to the full power
lets say you have a 2000 watt rms amp
and the 12s handle 600 watts rms a peice and the 10's handle 400 watts RMS a peice the 10's are likely to blow beacuse they are being over maxed on power.
but it can be done if you bridge them all.