Don't bet on it. Personally, I think most critics weren't in love with the film even if they did the research on how Astro Boy came from being a '50's icon to just being an average superhero in a world that pays more attention to glory hogs such as Miley Cyrus and the cast from Twilight. While some of us remember who he was and what he stood for, chances are that some people could care less for the film despite being number 8 in its first week in theaters even though the film was heavily advertised from Cartoon Network to ESPN. Personally, the film was empty as I stated before in the Astro Boy (2009) Discussion Thread. The same goes for 9, another animated film that I wouldn't mind seeing again or maybe owning due to how the animation is pretty good even if some of the critics weren't that crazy about the story.
So I will have to agree that Miyazaki, Disney/Pixar, 2-D Disney are already at5 the top pier of who will be nominated for Best Animated Film category for next year.