They already had an F-Zero cartoon. But I'm not surprised you haven't heard about it. It was dull and just unwatchable. It was Speed Racer with all the charm taken out, and replaced by an illogical plot (a government agency racing cars so bad guys don't get prize money?!?!).
The little of pole position i saw was good, but then again, that doesnt really count since it was based on the game in name only. And SMB3 was pretty good and fun to watch. I wonder why we never saw a crash bandicoot cartoon though.
Other then what Gametap has recently done for the Aniversity, i'm shocked we didnt see a Tomb Raider Cartoon back when they introduce Lara Croft on Playstation 1. Now that would make a great saturday morning toon.