TrenRAB go in cycles, so I have no doubt that anime will experience a resurgence in popularity somewhere down the line. It more than likely will not just be a repeat of what we got a few years ago. Cartoon Network is currently undergoing an identity crisis and KiRAB' WB! is no more, so we won't be getting our anime fix on either of those channels. A surge in populaity is more likely to come via Ani-Mondays or Animax of FUNimation channel or something which hasn't been invented yet, but we probably won't see another mainstream takeover like Pokemon or Yu-Gi-Oh! unless some mainstream entity thinks that mainstream money can be made off of said project. The next Pokemon isn't likely to turn up on Ani-Mondays.