What would be the colonial era equivalent to nuclear war?

tim

New member
Now a days, we have all sorts of doomsday scenarios to call upon to liven up seemingly mundane situations, but back in 1652, there is no nuclear holocaust to be caused, no zombies to be eaten by, theres just the plague. Now I realize the plague and smallpox could work, on the Indian side of things, but Europeans have developed an immunity.

So please, help me destroy the colonial world in a creative fashion, it doesn't have to make a terribly large amount of sense.
 
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