Your standards are...interesting. You obviously don't think the word gay is as insulting as the word retard, otherwise you'd be talking about the g-word right now, not the word gay.
Words have no inherent meaning beyond what context gives them. One thing that bugs me is that people have no concept of irony: if you'd notice, most of the characters who use those kind of words in offensive ways are characters we're SUPPOSED to think are stupid.
I get that these are your standards, and that's rad, but...come on. Really? You're going to pretty much eliminate any potential for irony-laced humor because you don't feel comfortable saying the word retard? Some people ARE people with limited vocabularies...or will your cartoons not have characters that're relatable everymen?
And again, a bizarre double standard. No jokes about religion, but your standards don't include "Don't mock atheists." Because atheism is not a religion. So...might wanna adjust your rules a bit. Sure don't want to offend anybody in your cartoon intended for grown men and women.
(I'm a theist, by the way...I also think ANY comedy is fair game. It's all about how you construct the joke. We live in a strange world where irony and postmodernism magically happened, we all can take a little jab at ourselves every now and then).
I have less issues with this.
As for my own standards? Depends entirely on what the show would actually be. And if I had to think of a few of my ideas...some would need more older themes than others.