My favorite animated TV series I have on DVD is Futurama...I have all five volumes and the four movies(my most watched episodes are "The Sting","Leela's Homeworld","The Devil's Hands are Idle Playthings","Rebirth","Roswell that Ends Well" and the "Bender's Big Score" movie)....I just love this series (It's very funny,but it also has touching/sad moments,and a cast I really enjoy)...
I also love my Looney Tunes Golden Collection volume 2 (which has my all-time favorite Bugs Bunny cartoon "What's Opera,Doc?" in the set) ,and my Mickey Mouse in Living Color volume 2 set (which has "Mickey's Christmas Carol","The Prince and the Pauper" and "Runaway Brain",as well as a nice interview with Wayne Allwine and Russi Taylor)
Movie-wise,my most watched DVDs are...
The Nightmare Before Christmas...I really love the songs...
The Last Unicorn....I think the animation is amazing,plus I love the dialogue (I've held on to my older copy of the DVD,even though the transfer is nowhere near as good as the 25th Anniversary,since the latter cuts out most of the swearing...I heard the upcoming Blu-Ray combo pack will be uncut,so I'm looking forward to that)...
Cats Don't Dance....Just another movie that I really love the songs for
Beauty and the Beast....My favorite Disney movie...For having awesome music/songs,characters,and story...