The vibration in my 2008 C50 starts around 50 mph, by 60 it vibrates my feet off the floorboards, and at 70-75 the entire bike vibrates very bad. The vibration is in the engine, I have found through infrared, vibration analysis, and ultrasound testing that one cylinder runs much different than the other. I think the difference is what is causing the vibration. I am a Reliability Engineer and certified in the above technologies and have used them to detect industrial machine problems for the past five years. I do not profess to knowing much about motorcycle engines, I have owned several different bikes over the past 35 or so years and have never had a problem like this one. I have ridden both inline and V-Twins, my last bike was a 1999 Suzuki Indruder no problems with it, great bike.
Around 70 mph you will not want to stay on the bike more than 5-10 miles, I have taken it to two dealers twice each. One dealer says there is nothing wrong with it, the other says the vibration is present, and it is in the engine however they cannot (or will not) do anything about it, and Suzuki so far has refused to do anything. While I like the bike it is useless to me at this point.
Allan