Hmmm. I've watched a lot of soaps. LOL.
My all time favorites:
Sonny and Brenda from General Hospital (there has never been more chemistry. Ever.)
Michelle and Danny from Guiding Light (Joie Lenz ONLY)
Those are my absolute top two.
Other favorites:
Jax and Courtney, General Hospital
Caleb and Olivia, Port Charles
Kevin and Lucy, General Hospital and Port Charles
Bo and Hope, Days of our Lives
Jonathan Jackson's Lucky and Elizabeth, General Hospital
Nick and Sharon, Young and the Restless
The original Billy and Mac, Young and the Restless
Carly and Jack, As the World Turns
Old school Ridge and Taylor, Bold and the Beautiful
Dinah and Hart, Guiding Light
Alan-Michael and Lucy, Guiding Light
Dillon and Georgie, General Hospital
I've liked a bunch of others that I stopped liking somewhere along the line, usually because I stopped enjoying one of the characters, like Ned and Alexis from GH, Nikolas and Emily from GH (I really liked them early on and a couple of their early scenes are still some of my favorite soap moments like "I'll be waiting for you" and "God, I love you", but then that turned into a mess), Alison and Jamal from Port Charles (I loved them...and then I hated Alison for what happened with Rafe), etc.
I was the most invested in General Hospital, therefore most of the couples I hate come from there.
Jason and anyone (especially Elizabeth, but I am not lying, with ANYONE. I despise Jason)
Sonny and Carly (emotionally abusive mess)
Sonny and Lily (oh, how I rejoiced when she blew up)
Sonny and Sam (ugh)
Jax and Sam
Nikolas and Courtney (ruined my Casper

)
Alison and Rafe from Port Charles
Lucy and Ian from Port Charles
Michelle and Jesse from Guiding Light (that was just laughable)
Hart and Cassie from Guiding Light
Michelle and Danny after Michelle was recast (that should've died when Joie left)