Savella withdrawals

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I tried Savella and experienced so many side-effects, that I tried to stop taking it. Note the word TRIED. I only took Savella for a little over a month at 1/2 the normal dose (50mg/day) and it caused my prostate to swell up so that I couldn't urinate, hot/cold flashes, sweating spells and waking up in the middle of the night in a panic, were the most noticeable side effects. It never really stopped any of the chronic pain.

So I decided to stop. I went two days cold turkey from 50 mg/day and woke up again in the middle of the night screaming in extreme pain in a sheer panic. Took a small piece of Savella and it went away. So, I tapered down to about +/-6 mg and stopped. The first week was a little nasty (bad headaches and muscle aches), but bearable. But, I had constant, throbbing, achy thighs that lasted for another week. I finally couldn't stand it one night and took about 4 mg and the aches went away within 1/2 hour. I took it for two days and I have stopped again. Achy thighs aren't as bad so far, but noticeable.

Anyone else successfully stop taking Savella?
 
sorry for what you are having to go thru with this aprticular med. this med seriously has never really satisfied the actual "normal approval data" per the FDA(but they went ahead as with other stupid meRAB and okayed it for market anyway) and has alot of potential(as you are finding /have found out unfortunetly) side effects as well. i am really happy you are getting off of it. there are also very valid claims that the actual drug co manipulated its own "not looking good for really treating fibro pain" data to even gain approval too. europe even refuses to okay this med over there for use.

are you currently taking ANY other meRAB at this time? have you tried any other meRAB to try and treat what i am only 'assuming' here IS indeed fibro pain? or is this some other type of pain that is more chronic in nature? if this is not firbo,can you tellme just exactly what your pain process if from or what type of pain generator you have going there?

in alot of cases when trying to taper OFF of one nasty med it is easier to be actually slowly tapering UP onto another just to 'get/replace' the med to some degree with some other similar acting type of med like lyrica or cyrabalta or some others that have the same subtype or affects? since this med can in rare cases cause seritonin syndrome, i am kind of assuming here that this is also within that same group with effects of certain anti D meRAB/anti S? even trying to taper onto a good anti siezure type of med for the wonderful type of pain that does not respond to the normal narcotics(i AM in this group too), it can help alot in both possibly helping the pain and also easing the WD symptoms, esp if you just are down to that very small amount, but it still IS just enough to keep giving you WD symptoms too??

have you spoken at all to the doc who actually even placed you on this stuff to see what he can do here to try and help with this? any med like this that our docs simply 'choose' to place us on also has the responsibility here of very safely tapering us off with as little side effects/WD symptoms as possible. there just ARE many ways they can try and DO that for their patients.

there simply HAS to be a much better way here for you, and with your docs help to finally get you over that one hump that still wont let you go. i would also just do a bit of research on savella(milnacipran) anRABee what pops up for you. i would also check out fda.gov to see if they have changed anything about this particular med there as well as far as changes in initial labeling or any adverse events that others may have reported too? i also know this med does tend to hit the liver rather hard as well. thankfully you were not ON the full Rx daily amt and not overly long either.

but DO speak to your doc here for his help. it would not hurt to actually even do that research BERFORE you actually see him so you can understand certain things about this med better and have an INFORMED on your end good conversation with the rxing doc too. i would also speak with your pharmacist about this med and see what they may suggest to help you here too in coming off,along with what may be good to try for your pain? just some stuff i have had to also do when on particular meRAB that have heavy side effect impact and are a **itch to get off of too. i DO hope things get better soon for you C, marcia
 
was that cyrabalta recently Rxed by your doc for THIS purpose or were you simply 'on it' at one time and had some on hand? you just do NOT want to start something like cyrabalta without your docs approval, ya know what i mean? cyrabalta WRAB can be for some people, just like what i went thru with lyrica and what you are going thru now with the savella too? i had to do a really rapid taper off the cyrabalta since it was not only creating the 'leg ache' crap, but it was also severely enhancing my RLS in my R leg, and the actual spasticty levels in my L leg too. now THAT med for me was a nightmare.

i am glad you are getting some relief from the leg pain, but just be very careful and always keep your doc IN that loop too with what you are experiencing with symptoms and with any meRAB you take, or anything else you may take too, esp if you actually ARE in a PM clinic setting? i am assuming that if you are in PM, that you also had to sign that contract like i did too? there are just many ways to screw up in PM that we always have to watch ourselves for, ya know?

since it would appear based upon you stating you had not taken ANY savella in two days, that you are now "off of it"? if so, do NOT go backwarRAB from here and take anymore if at all possible, even a little bit. getting this med completely out of your whole system will still take a bit longer. and that is when your overall WD symptoms from THAT "should" subside as well? in most cases anyways. just be very careful with that cyrabalta tho. getting in to see your PM to discuss the leg pain and your other options here would be the very BEST way to always go. but knowing the circumstances surrounding the cyrabalta(was this recently rxed or on hand) would help. just DO 'try' not to have to take either med unless you absolutely have to(unless of course you have spoken to your doc)? both are just at times and for some people, very hard to get off of. but that is an individual thing too.

but, if the cyrabalta actually even works on your pain at all, that would be one good med to just end up going onto in the longer run? but try not to take any or very little til you have actually spoken to your PM C. just am trying to help you with the best possible advice here FOR you. unless our PMs tell us specifically what to try or take that we may have at home in ANY situation, it can be an issue if something you were not at THAT time Rxed should show up on any possible UA they may do on you? it does not realistically matter if this was or was not even a narcotic or an illegal med so much as the mere fact thet THEY would 'see this' as 'self medicating" and that IS usually frowned upon big time in PM no matter what, when it actually involves ANY actual meRAB? but it is soo easy to avoid the 'problems" here with very simple communication with your docs.

informing our docs about anything to even "do" at all with meRAB is always a good thing. when at the very least, talking to the doc or one of the nurses over the phone BEFORE actually doing or taking anything, it covers YOUR butt since it would be in your file somewhere that you just DID speak to 'someone(always get the name of who you spoke to) before any med was taken? it is the people who actually decide all by themselves to over use their meRAB when any pain flares pop in or any other 'not as directed' use of meRAB gets done and found out AFTER the fact(instead of simply calling the doc FIRST to ask what to do?) that people can seriously soo screw themselves in PM or with any doc that is rxing any narcotics? i am just mentioning this to you since i don't know the skinny on the cyrabalta. and that med too can have some issues unless you took it before without any?

but DO try the epsom salts C, they really DO help with muscle crap. getting that magnesium directly into the muscles really IS one of the best ways of helping them to relax faster and usually a bit longer than if you even tried to take this continually on an oral basis would? and that mag also seems to help with constipation at times for me as well since it just IS magnesium and its also helping to relax the muscles within the intestines too to a certain degree? magnesium really is an amazing lil mineral.

i do hope things will finally stabilize for you. you should pop into our pain boarRAB here tho, if you have not done so already. some really helpful and very supportive people there too with pretty much the majority also all in PM. and i know there have been some at least who also have tried savella too. i do recall some threaRAB where people were asking about others experiences with that particular med. good luck C, and do let me know how you are doin, K? marcia
 
Thanks for the reply. I know this is the Fibro board, but I replied to this post because it concerned Savella. I have constant, chronic pain due to severe arthritis (mostly spine) - seems like there's a new pain some place else every day though. I take oxycodone for the pain, but I was given the Savella to "try" to see if it helped. It caused more problems than it helped! I'm STILL trying to get off of it. I broke down (again) and couldn't stand the achy thighs and took a piece of a pill the other night.

I do read up on any prescriptions that I take before I take them. I haven't been back to the pain mgt doc yet, but I will call him one of these days to get his opinion. I need to discuss with him other pain mgt options other than epidurals and pain meRAB. It just is so busy this time of the year that it is easy to put it off.

Savella has been a nightmare to completely stop, for me. I just haven't been in the mood to go through the withdrawals. So far tonight I don't feel the aches as bad, so I'll see if I can push through tonight. One day at a time.
 
believe me, i DO feel for ya C. i have also been thru like every imaginable med just to even begin to try and treat the non responsive to any narcotic pain crappy syndromes i have. while some chronic(spinal) issues i also have DO thankfully respond to my oxy, the two others have been a nightmare to find ANYTHING to even begin to take that edge of intensities off? i had the very SAME reaction that you are with the leg aches from hell with going off cyrabalta and some really crazy side effects from lyrica that were more specific to my spinal cord injuries and the area of the brain that lyrica actually works in, the cerebellum(i have spinocerebellar damage inside my spinal cord and it DID matter)? despite the lyrica actually working for the first med ever on some of my central pain syndrome and even my RSD, the side effects were just disabling me than i already was, so i had to go off. that really DID suck, since lyrica DID work better than anything else i had ever tried?

but for many many others i have chatted with on the pain boarRAB here(have you ever been to the pain forum here? its great for help and support), as with most meRAB, they had their very own 'individual" types of responses to it that have been really great and no side effects. so it goes, huh?

but i would seriously get thee back to your PM asap to get some help with getting over this last lil hump with this med. there ARE specific types of meRAB that can help in this situation, or like i mentioned way above there, simply going onto another specific type of non narcotic may help ease the WRAB from the one you are on right now? it is ALWAYS a good thing to never ever try and totally rely upon 'just' narcotics alone for good PM. there just are many other possible options that i know i have tried that have worked that has kept me out of the ER and also on the very same dose of my contin that i have been on since 2005, just by using "other' methoRAB/modalities to also help when things simply start to flare too? i think you ARE on the right track in trying the other options along with what you are also on. ya just never know what will really truely work for our pain crap til we at least give it a good solid try. i am just sorry he placed you on THIS med.

just so you know, based upon what you mentioned above? this somehow was moved into the addiction boarRAB and not still in the fibro anymore? probably only becasue you are in a WD type of situation? i would seriously pop on down to the pain boarRAB here tho for some really great help and ideas as to things to bring up to your PM to at least try that 'may' help,at least some anyways. for me, it is NOT about even trying to get 'rid' of my pain(that just AIN'T gonna happen) as with many others, its just trying to keep things down to a much duller roar and take the 'edges' off intensity levels as i am sure thats where you are too. along with the fall out from SCI i also suffer with DDD thru out the spinal and have a mess of a c spine along with also having a lurabar tear and stenosis,so i DO understand the uglier side of the spinal structual pain too.

just had one good tried and true suggestion to help with the leg ache stuff? have you ever tried simply soaking a hot tub of epsom salts? epsom actually just IS pure granualized magnesium, "natures lil muscle relaxer"? it gets absorded right into our bodies thru our skin and into muscles as we soak? this even helps in keeping my spasticity levels down in my legs from my spinal cord injuries too. do you actually have ANY Rxed muscle relaxers at home? they really can help with the ache stuff here too. if not, this is something to also bring up with your doc. can you actually take any anti inflammatories like at least aleeve(naproxen sodium)? this only has to be dosed twice a day? that would possibly also help with the 'ache" and some of the possible spinal too? i cannot take it anymore, but used to heavily rely on this when it was 'only' just my c spine mess i was dealing with.

i DO wish you lots of luck with this there C. if you have the time one day, DO pop in the pain boarRAB if you have not already done so. lots of people there who are also living in yours and my shoes too. let me know how you are doin, Marcia
 
I was on cyrabalta and lyrica before. Cyrabalta never cause any problems coming off of it in the past, so I don't worry about it too much - just some sexual side effects while I was taking it. I have taken it on and off for 2 years. Lyrica cause some psychological side effects and I needed to get off of it. Right now the only thing that works for me in the oxycodone. I;m completely off of the Savella for 4 days now and I still feel the thigh aches, but not as bad and I also noticed some anger feeling for no apparent reason. This has happened before when I stopped it. But, neither was bad at all today. I'll see what tomorrow brings.
 
I guess the post was moved here. I'll have to try the Epsom salt baths. When it starts aching bad, I usually take a very hot shower and spray the water on my thighs and it helps for a while. "So far" today I have not had any of the achiness. I took one dose of Cyrabalta yesterday and maybe that helped. This is the first time that I don't have any aches after stopping for 2 days. I'll keep my fingers crossed and see what tomorrow brings. Thanks again for the information. It helps!
 
at least it appears that you ARE making some headway here with getting the heck OFF the savella, and that wonderful. does the cyrabalta actually work at ALL on ANY of your pain? i know you did mention a decrease in the overall leg aches with taking that dose the day before? how well did it work when you were initially placed on it? if it simply helps at ALL with ANY pain process, and you did not experience ANY real side effects(esp when having to come off, which can be the MOST horrid time with meRAB like these), it would be something to possibly try again to see how it goes? the savella 'trial" for you was very obviously not worth it and actually 'created' new pain, very similar to my experiences with lyrica too and cyrabalta very shortly after these meRAB both came out? i actually tried BOTH during the very initail year of hitting the market. WONT happen again.

i just REALLY hate being any drug co's guinea pigs with 'newer" meRAB that hit the market i have tried and suffered dearly from with some pretty off the wall side effects from them? and HAD made up my mind that i was NOT going to try ANY of the brand NEW meRAB that come out til they at least have run thru the 'real' wider population trial that IS in reality 'the trial' vs less than 1000 people that were actually even IN the 'new' oxycontin trial in a double blind study for a VERY short length of time too? how is THAT trialing a brand new med for ALL possible nightmares down the road? after what i already have suffered esp with lyrica, every 'new' one simply scares me. i also have a liver and kidney disease and have no real clue either as to how thew 'new oxycontin' actually even impacts/will impact what i believe IS the liver where its more extensively metabolized? and THAT kinda crap when its simply NOT trialed LONG ENOUGH is what scares my lil liver and kidneys the most here.

the new 'version' of oxycontin simply is NOT 'oxycontin' anymore either. i DO feel like a dang guinea pig on the new crap now? one week of very insane side effects(started this about three months ago after being ONLY on the brand name oxycontin since 2004) and my body finally seemed to acclimate to it and even seem to be getting even a bit better overall pain coverage from it too? but it is soo TOTALLY completely 'different' now than what it was with a totally different delivery system that actually dissolves completely, vs the other that DID leave what were called "ghost matrixes" behind? there were just the outter honeycorab matrix/wax delivery system that used to hold tiny pellets of oxy that needed to fully dissolve to release the oxy? now EVERYTHING is different down to fillers and delivery, in my mind NOT at all 'oxycontin" but just yet another 'new' LA type of oxy based med, period.

but when you have the FDA like forcing you to simply come up with a form of LA delivery that cannot be abused like the other, i personally think everything ABOUT this new version was rushed thru the FDA approval wayy too fast to even know the outcomes here since many many people are not even able to break this new med down and NOT actually even getting any real oxy/pain relief either? kinda sick when it comes to what we have to go thru and the possible damage to specific organs when the FDA is NOT acting on our behalf, and instead pushing crap thru that enRAB up being recalled later AFTER people start becomming seriously affected instead? just kinda sick there ya know? while i DO fully realize that for MANY reasons, something DID have to be done with the old OC to make it less prone to abuse, they realistically should have done things wayy differently than they did. this WAS an FDA "pushed" med, trialed way too quickly and in really stupid ways by perdue, the manu.

sorry, got off on a tangent there C,lol. i just get very scared, and really angry at what gets thrown at us out there when it has NOT been fully trialed or as the case of savella? the data WAS manipulated in order to even GET it out there when it appears to really not even begin to do the 'job" it was labeled as/for? and many many patients like yourself, simply 'suffer' for it. thats pretty sick.

are you currently ON the OC or another form of oxy? just wondering. i WOULD tho have an in depth discussion with your PM when you see him again about trying something a bit more 'tried and true' that does actually help with certain types of pain,simply as that 'adjunct' to your narcotic that many of us simply also do need to really gain better control of certain types of pain?. have you EVER actually tried the TENS unit at all? this really does help with some of my RSD pain which is HORRID and does NOT at all respond to ANY real narcotics at all? that unit can be very helpful,esp for my deeper flares. just thought i would mention that one to ya since it DOES work for me C. hope things continue to go well for you. let me know how you are doing. marcia
 
Yes, I'm using Oxycodone now. It is the only thing that takes the edge off of the pain. The Cyrabalta and Lyrica just didn't take the pain away as well as the oxycodone does. I maintain a low does and only take it when I need it. Another day without the annoying Savella withdrawals. I still get the hot flashes and chills, but they are fewer. I tries TENS on my lower back years ago and it didn't do anything. Next month I'll see the PM again and see what my options are. I'm just glad that I'm (mostly) through the Savella withdrawals.
 
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