Ugh, yes. I'm still shocked that made it onto the air.
Everything on Superjail.
Spongebob stepping on Plankton in the Spongebob movie, then slowly scraping his foot on the ground, while Plankton can be heard wailing in agony.
Mung Daal getting slashed by a bear in the Grubble Gum episode of Chowder. Cut to the next scene, his nose is almost ripped in half, a large chunk of his nose is just barely hanging onto the rest of it by a tiny piece of skin.
Meatwad using a chainsaw to cut Master Shake's tongue off.
During a parody of Jackass on Family Guy, Johnny Knoxville gets shot in the face with a shotgun, blowing off the right side of his face (Think Two-Face from The Dark Knight, only ten times worse)