I had it today. I made it to stage four, then dropped 20 percent, so they stopped the test and gave me the asthma diagnosis. They give you 5 doses, and if you drop 20, in the first three, you have asthma. If you make it to 4 or 5, your doctor will talk to you. I made it to 4 and could really feel the bronchoconstriction. Here is some information that may help"
Methacholine (METH-ah-CHO-lean) challenge testing is used to assess for asthma or airway hyper-reactivity. This test is usually performed when asthma is suspected, but spirometry does not indicate its presence. Methacholine provokes bronchoconstriction (airways tighten), which is then measured by spirometry. Patients with asthma will typically respond at lower doses. This test has a high negative predictive value (i.e. if the result is negative, then there is likely no asthma).