LPR link with Ibuprofen debate?

  • Thread starter Thread starter Jay Jacob
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Jay Jacob

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Some other meraber (cant remeraber) stated that they went and saw a physician about a focus on the "C5" in the neck column. Massage or some of chiropracting etc..... they said it was a neurological problem. They have seen a real big improvement.

I am a big fan of Shiatsu therapy (I don't like needles from acupuncture) so I am going to ask my dude that does it to maybe give me some focus in the neck area.
 
As a beliver that I may have obtained LPR from taking Ibuprofen (for a viral infection)....

Does this mean that I will have an Ulcer caused by taking Ibuprofen; a duodenal ulcer. I have had previously the test for H Pylori but I did not have it.

I ask because according to what I have read PPI's will make the ulcer go away. I have tried PPI's several times at various dosage, but they have seemed to have not worked and due to frustration and bad things read about them - I have always quit them after a few weeks....

Has anyone had a success story or thoughts that they can share?
 
Ibuprofen is known to cause stomach and duodenal ulcers, but i cant see how it would cause LPR.

If you had an ulcer from taking ibuprofen, and took a PPI for between 4 and 8 weeks, there is no doubt it would heal.

if you are still getting symptoms, it might just be functional dyspepsia (the symptoms are more or less the same as an ulcer), treatment is a PPI or simple antaciRAB.

Have you had an endoscopy or upper GI X-Rays?
 
I have had Barium Swallow. Nothing came of it. I could have upper enRABcopy and this has been on the carRAB. I am new to the forum but not with LPR, I am 27 and have had it for 4-5 years now.

I have tried many things:

DGL Lic and Digestive Enzymes and Psylium Husk fibre has been the best so far.

But determined to find a cure.
 
my huband test neg for H-pylori and took the antiabiotics anyway and felt like a new person after 30 days
 
Sunrise, where do you see that Lyrica is a GABA agonist? I've done alot of searching and no study has confirmed this is the case.

I've found studies that confirm GABA agonists significantly reduced TLESER's in dog's, however can not find any specific drugs that are GABA agonists.
 
Hi Jacob,

Nice to meet you and thanks for the encouragement. I'll be sure to keep you all updated, even if/after i get out of this mess.

The length of your time with it, 4-5 years, seems like it really could be laryngeal sensory neuropathy/nerve related.

For one thing, it's not common for this to happen to guys, and in their 20s, but when it does it seems to begin with a bad cold.

A lot of people blame it on the ibuprofin and stuff, you can see in other posts, but really they were taking ibuprofin because why? Because they were sick. I think the virus/cold/flu is the real culprit of the whole problem.

For one thing, your barium swallow showed no reflux. I bet you don't really have reflux, and if you had surgery, it seems like every time, we 20 something guys wake up from it clearing our throats.

However, since it began with a cold which is a virus doing damage to tissue in your throat, it makes more sense that somehow the virus did damage to nerves in the area, and put them into a state.

In any case, you gave the first idea 4 or 5 years to work, and it didn't. So why not talk to your doctor about laryngeal sensory neuropathy, after doing a little investigating.

Especially for us 20 something guys (quite a few are from the UK) who got a cold, and then suddenly have chronic reflux (?), it seems like our medical neeRAB are being neglected.

There was some australian guy who had a disease where he is allergic to sunlight, but growing up, his doctors and family all thought he was some kind of hypochondriac or mental case. Now they know. It was physical.

Right now, we are the people probably suffering with some poorly or totally not understood medical condition. We have to really push to get to a cure, and the diet stuff is just adding stress, and giving doctors an excuse to send patients like us away without solving our problem. I'm at the point where I would happily volunteer for nerve surgery experiments just to try to find a real cure to this, instead of a no carbs diet, and other medieval superstition sounding garbage. I find eating what I want took a lot of the irritation of having this disease away.

P.S. I don't have to wear a tie, but my coat pressing on my throat bothers me, so I can relate.
 
gabapentin (aka neurontin) is a gaba a agonist.

Since pregabalin is it's successor drug, which was basically an improvement on it, I assumed it was also a gaba a agonist. Is it not?

Keep in mind, baclofen and these other drugs which inhibit lower esophageal sphincter relaxation are gaba B agonists (right?) which is a different thing. The point is "gaba" is a substance that is carried along the vagus nerve, which is where our unpleasant symptoms are carried from.

p.s. have you ever heard of people who went to a chiropractor who kinked their neck, and they swear their LPR went away. I have. I've also heard of one or two who got their LPR immediately at a chiropractor appointment. Nerve related?

Hmmmm..... I guess I shouldn't have smoked all night. Anyway, xhale, you just want answers and relief, like me, so I'll try to learn more about this GABA and what is all about for you and myself.

My belief in pregabalin's potential to help is largely based on the work of three ENT doctors whose last names I will now list: Morrison, Sycamore, Woo. All in North America.
 
really important to add:


there is not one doctor in the world today who really knows why gabapentin and pregabalin work.
If my scientific knowledge is fradulent on this, so would be the science of any doctor in the world.

There are only theories on why it works, which means (like most great discoveries) it was completely by accident that it was discovered. Just like penicillin was discovered by accident.

Neurontin and lyrica relieve hard to relieve pain/neuropathy and no one in the world knows why they work yet.
 
So how long were you on the Ibuprofen? Alot of my problems with the sore throat every morning started after I took Ibuprofen for my wisdom teeth removal. I was taking the equivilent of 12 advil a day for around 10-12 days. The sore throat every morning started shortly there after. This is when I went to the gastro doc and he found moderate gastritis after I had an endoscopy.
 
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