Rachel Joy Horn's breasts were ticking time bombs. She lost trust in her body and no longer felt comfortable in her own skin.
This is how she felt, she said, when her doctor broke the news to her that she'd tested positive for a gene mutation that put her in the high risk category for developing breast cancer. So at the age of 21, Horn chose to undergo double mastectomy surgery to remove both her breasts – and hopefully, the future threat of cancer.
"By the time I was tested, my mom had gone through breast cancer twice so I already had it in my mind that surgery was a possibility for me," Horn said.
Horn is certainly not alone in her decision. Stars like actress Christina Applegate, talk-show host Sharon Osborne and most recently Oscar winner, Angelina Jolie have revealed they too have chosen to preemptively removed their breasts due to a strong genetic predisposition for breast cancer.
Jolie's Double Mastectomy Decision for Kids
It sounds like an extreme choice but a woman who has inherited a harmful mutation of either the BRCA1 or BRCA2 gene is about five times more likely than average to develop breast cancer and up to 40 percent more likely to develop ovarian cancer, according to the National Cancer Institute. Experts increasingly believe that removing as much breast tissue as possible can be a lifesaving strategy.
Tickingtimebombs.com
Rachel Joy Horn opted for a double mastectomy... View Full Size
Jolie Writes of Pitt's Full Support for Mastectomy Watch Video
Jolie's Double Mastectomy Decision for Kids Watch Video
Angelina Jolie Undergoes Preventive Double Mastectomy Watch Video
As Dr. Mehra Golshan, Director of Breast Surgical Services at the Dana-Farber Cancer Institute in Boston explained it, "For women who know in advance there is a good chance they will develop breast cancer sooner or later, having prophylactic surgery can make sense. It lowers the risk of developing cancer by more than 90 percent."
In one recent study which followed nearly 2,500 women who carried one of the two dangerous gene variants, having a double mastectomy did appear to lower their risk of breast cancer. None of the women who opted to have their breasts or ovaries removed were diagnosed with breast cancer in the three decades they were followed, while 7 percent of those who chose not to have surgery were.
Horn said that removing her breasts gave her the sense that she had dodged a bullet.
"I remember waking up after surgery and feeling groggy but happy," she recalled. "I immediately felt relieved that I no longer had this cancer diagnosis hanging over my head."
Angelina Jolie's Mastectomy: What You Should Know
But even though the data shows a preemptive strike against breast cancer can improve the chances of survival in women with inherited risk, some medical experts are concerned that instead of fighting to save their breasts as they did in the past, many women are choosing to remove them at the slightest whiff of cancer.
The Journal of Clinical Oncology reported a 188 percent jump in the surgery between 1998 and 2005 among women given a new diagnosis in one breast of ductal carcinoma in situ or DCIS, the so-called "stage zero" cancer. Among women with early-stage invasive disease, the rates soared over 150 percent.
"Many women choose to have other breast removed to avoid the trauma of going through breast cancer again even though in reality the chances of reoccurrence are very low," said Dr. Julian Kim, chief, of oncologic surgery at the UH Seidman Cancer Center in Cleveland, OH.
This is how she felt, she said, when her doctor broke the news to her that she'd tested positive for a gene mutation that put her in the high risk category for developing breast cancer. So at the age of 21, Horn chose to undergo double mastectomy surgery to remove both her breasts – and hopefully, the future threat of cancer.
"By the time I was tested, my mom had gone through breast cancer twice so I already had it in my mind that surgery was a possibility for me," Horn said.
Horn is certainly not alone in her decision. Stars like actress Christina Applegate, talk-show host Sharon Osborne and most recently Oscar winner, Angelina Jolie have revealed they too have chosen to preemptively removed their breasts due to a strong genetic predisposition for breast cancer.
Jolie's Double Mastectomy Decision for Kids
It sounds like an extreme choice but a woman who has inherited a harmful mutation of either the BRCA1 or BRCA2 gene is about five times more likely than average to develop breast cancer and up to 40 percent more likely to develop ovarian cancer, according to the National Cancer Institute. Experts increasingly believe that removing as much breast tissue as possible can be a lifesaving strategy.
Tickingtimebombs.com
Rachel Joy Horn opted for a double mastectomy... View Full Size
Jolie Writes of Pitt's Full Support for Mastectomy Watch Video
Jolie's Double Mastectomy Decision for Kids Watch Video
Angelina Jolie Undergoes Preventive Double Mastectomy Watch Video
As Dr. Mehra Golshan, Director of Breast Surgical Services at the Dana-Farber Cancer Institute in Boston explained it, "For women who know in advance there is a good chance they will develop breast cancer sooner or later, having prophylactic surgery can make sense. It lowers the risk of developing cancer by more than 90 percent."
In one recent study which followed nearly 2,500 women who carried one of the two dangerous gene variants, having a double mastectomy did appear to lower their risk of breast cancer. None of the women who opted to have their breasts or ovaries removed were diagnosed with breast cancer in the three decades they were followed, while 7 percent of those who chose not to have surgery were.
Horn said that removing her breasts gave her the sense that she had dodged a bullet.
"I remember waking up after surgery and feeling groggy but happy," she recalled. "I immediately felt relieved that I no longer had this cancer diagnosis hanging over my head."
Angelina Jolie's Mastectomy: What You Should Know
But even though the data shows a preemptive strike against breast cancer can improve the chances of survival in women with inherited risk, some medical experts are concerned that instead of fighting to save their breasts as they did in the past, many women are choosing to remove them at the slightest whiff of cancer.
The Journal of Clinical Oncology reported a 188 percent jump in the surgery between 1998 and 2005 among women given a new diagnosis in one breast of ductal carcinoma in situ or DCIS, the so-called "stage zero" cancer. Among women with early-stage invasive disease, the rates soared over 150 percent.
"Many women choose to have other breast removed to avoid the trauma of going through breast cancer again even though in reality the chances of reoccurrence are very low," said Dr. Julian Kim, chief, of oncologic surgery at the UH Seidman Cancer Center in Cleveland, OH.