I'll let my opponent dictate who I start. Cadillac didn't play last year so the jury is out on his effectiveness against the Cowboys. Last year Hightower averaged 1.65 yds/car in his two starts against the Niners, no way am I going with him. Start Cadillac Williams.
EDIT: I now hear that the Bucs will be platooning Cadillac, Derrick Ward and Earnest Graham (three way split), so don't go with Cadillac either. If you can, pick up a 1-week substitute, like Fred Jackson (Buf).