I HAVE A 1998 ford E250 V8 ENGINE MISFIRE COMING FROM THE 8 SPARk PLUG CLYINDER WHAT

Change the spark plug . If that doesn't fix it,check the wire. It should have no more than 20,000 ohms and if it shows a dead short ( infinite resistance) it's definitely no good. You could skip all that and just change the wire if a new spark plug doesn't improve things.
 
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