If there's a big difference in fares and time convenience, take whichever one of the three - LGA, JFK, or EWR (Newark-Liberty) that gives you the best deal and time.If it's virtually a tie, I'd say use JFK for its convenience. The $5 AirTrain, built for air travelers, will get you to Jamaica. There, you can get the $2 subway, or the Long Island Rail Road (fares vary based on time of day/day of week).On the subway, you can get a Manhattan-bound E train, and transfer to an uptown 1 train at 42nd Street. Take that to Columbia (or get an uptown 2/3 express, transfer at 96th, then get the 1 to finish the trip).On the LIRR, you can get to Penn Station and then get the uptown 1 (or 2/3 to 96th then the 1).But if you can get a steeply lower fare to LGA, it might be worth it to go there and just take a cab or the M60 bus and a transfer to the subway to get to Columbia.Newark is also convenient, with its AirTrain and connections to rail lines to Penn Station.Once you figure out your options, we can give you suggestions and specifics.