it depends on what type of filter you have. if you have a filter which gives you different chambers for media ie; ceramic beads, foam, carbon etc, then i recommend you only replace one media at a time. ie; one week, remove the carbon, in two weeks, remove the ceramic beads etc. if you have a filter which has those horrid cartridges that are just floss filled with carbon...well, you dont have much option other then to change it all at once. in this case make sure you do not disturb or clean out the bacteria that is in the filter itself.