Well, let's see.
On DVD, I have...
One Piece ~ I'm currently four volumes behind; only up to S2/V2. I'll probably buy the next two with the current RightStuf sale.
Death Note ~ Got the first full box set last Christmas, and the second this Christmas. I saw it all on [adult swim], though, so I'm in no real rush.
Now and Then, Here and There ~ I saw the first half on Animonday, bought the DVD release from RightStuf MONTHS ago, and still haven't gotten into it.
Last Exile ~ Heard good things, bought it from RightStuf, still haven't started.
Romeo X Juliet ~ Heard VERY good things, got the first volume for Christmas. I intend to buy the second half before I start, though.
Giant Robo ~ Heard INSANELY good things, got it for Christmas. Very much looking forward to this one.
Mushi-Shi ~ Saw the first episode online, liked it a lot, got the full series for Christmas.
That I still need to buy (and this is only stuff near the top of my list)...
Big Windup! ~ Which I still haven't bought, but, still. I watched the first few episodes online and just knew I had to buy it.
Baccano! ~ Watched the first episode online and now I really really really need to get it. Now that they've released a complete set, I'll be picking it up soon.
Samurai Champloo ~ I've seen a few episode here and there, so, yeah, been meanin' to nab this. But I'm not sure if I want the Blu-Ray or not; I've heard some less-than-ideal talk.
Fullmetal Alchemist ~ Which I've seen, but would like to watch again. I'll probably get the box sets EVENTUALLY. I'm in no real rush.
Gankutsuou: The Count of Monte Cristo ~ Looks like such a trippy, weird series, and I love seeing Japanese adaptation of Western media.
Outlaw Star ~ Saw back in the day on Toonami. I'd like to revisit it.
And shows I'd like to watch online before buying...
Gurren Lagann ~ Seen the first... eight episodes. I'd love to buy it but there's like five releases and I can't begin to wrap my head around them.
Casshern Sins ~ Because it's supposed to be really good AND I'd like to familiarize myself with the character before Tatsunoko vs. Capcom.
Monster ~ I've heard good things. Hopefully they add more than the first episode at some point.
Soul Eater ~ I'll get around to it, because it's supposed to be good, but I don't really feel it, to be honest. Maybe I'll wait for the dub.
Other shows that I want to see released, or put online before I make a full purchase. A lot of 'em are on Crunchyroll, yeah, but I absolutely loathe their video player, and just can't get in the mood to watch long-running shows online, unless they're, like, weekly updates or something.
Fist of the North Star ~ It's absolutely fantastic, but, WAY too many episodes to watch online.
Slam Dunk ~ Same as above.
Eyeshield 21 ~ Same as above the above.
Le Chevalier D'Eon ~ Seen the first episode. Seems nice, but, not sure if I'd like to get it yet.
Tsubasa - RESERVoir CHRoNiCLE ~ It looks really good, but I've only heard mixed opinions, so... who knows.
...and that's not even counting movies and shows I'm thinking about buying at some point. This is just, like, immediate attention. Jeez.