It seems like "South Park" is pretty in right now, at least with high school kids. I would go to school the day after a premiere, and everybody (I'm not kidding) would be quoting last night's episode. Even to the point where after "Canada on Strike" aired, somebody would yell "I'm not your friend, buddy!" and then somebody on the other side of the hallway would yell "I'm not your buddy, guy!"
Same with Family Guy, although I personally don't watch it.
And of course, Pixar movies. They're considered cool no matter what age you are.