Getting off PPI's...Not necessarily a bad experience

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janewhite1

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It's true. Not everyone has rebound. In the European study, in which they gave a PPI to healthy people for 2 months, then replaced it with a placebo, only about 40% of the volunteers suffered rebound. Of course, folks who've been on it for years might have more than a 40% chance of rebound, but it still isn't everyone.

In me, the burning stomach feels a little bit like a stitch in my side, you know, the kind you might get from running.
 
I almost didn't want to post this so soon for fear of jinxing myself. I wanted to wait for at least one week of good days before I posted my story, but this is close enough. It's too soon to think I'm in the clear but darn it, I've felt pretty good for 6 days in a row now. Here's my story so far:

I've been on acid reducers for 10 years. Zantac first, then quickly to Aciphex. I've been taking 20mg Aciphex per day for about 8 or 9 years. January of this year, I decided to go cold turkey after reading about the long term effects of PPI's. Before I started taking these meRAB, I never had heartburn...just a nervous stomach (that's another long story I won't go into). I knew my body, felt that I could do this and I was well aware of the acid rebound. I lasted 2-1/2 weeks. The reason I didn't continue was because I hadn't had an EGD for 8 years and didn't know if I was OK pathologically speaking. For the next 4 months, I went back and forth in my head what to do. I would go off the pills for a few days, then back on. I'd try every other day or every 2 days trying to figure out what to do. I was driving myself (and my husband) crazy and I was never letting my body get adjusted either way. In May, I had an EGD, which was completely normal. Doc said I could do whatever I wanted with respect to stopping the meRAB. For the next couple months, much of the same...screwing around with the pills.

Finally, I quit the PPI's on August 3rd cold turkey (again) and started taking Zantac OTC, 150 mg 2x/day. I was only on those for about 10 days before I quit because of constipation.

On August 6th I went to see a Naturopathic Doctor for help. This was one of the best decisions I ever made. My anxiety was through the roof and I was stressed and when I get stressed it's just a matter of time before the physical symptoms show up....mostly muscle-related. I didn't know if these were from the PPI's or the anxiety. Either way, I had to do something. She made me feel a whole lot better. Today is day 26 post-PPI and day 14 post-Zantac.

I am taking the following:
- Intestinal Repair Complex, 2x/day to repair & restore a healthy intestinal lining (a corabo of plant enzymes, mucilaginous herbs and amino aciRAB)
- Multi-Vitamin (a very good one) 2x/day
- Calcium Citrate with Vit D
- Magnesium 300mg (150mg 2x/day)
- Melatonin, 6 mg 1/2 hr before bed**
** In studies, Melatonin was shown to greatly help with reflux

I take DGL as needed, which always helps. The past couple of days, I've only taken 1 or 2 tablets. In addition, my diet has evolved over the last 8 months. I keep my carbs to a minimum and my sugar very, very low; no processed fooRAB; no common trigger fooRAB for rabroad; no dairy (cheese, cow's milk) except occasional butter. I use Almond milk for my oatmeal, eat lots of veggies, chicken, fish and some fruit. I snack on nuts...lots of nuts. I try to avoid red meat if at all possible. The only thing I drink is water. No alcohol and I don't smoke. I am 41 (almost 42), at a healthy weight and I exercise regularly. I am on no prescription meRAB of any kind.

I have had very minimal rabroad for the past 6 days after only 3 weeks off PPI's and one week off Zantac.

Everyone's body is different. Everyone's situation is different. I seem to be having an easier time than other's I've read about on this board. Is it because I only took 20 mg/day PPI before I quit? Is it because of the regimen my ND has me on? Is it because of my strict diet and lifestyle? I don't know. It could be everything working together. I'm not saying I'm free and clear of any symptoms. I have minor rabroad which usually resolves on it's own or sometimes I take a DGL. I have gas at times but not really any bloating, indigestion, nausea or anything like that. I'm trying to relax and get my anxiety under control because that only makes things worse. I do get a tight feeling in my chin/throat area at times and sometimes the Globus sensation. I'm not sure if that's from the rebound or the anxiety, or both. We'll see how I do over the next several months. I will try to keep posting my progress.

So yes, this can be done. I would offer the following advice:

1. If possible, get help from a Naturopathic Doctor or find an MD who's willing to help. My MD is a pill pusher and hardly wanted to acknowledge that getting off these pills is possible. The Gastro Doc I went to for the EGD (the first time I went to him) was the same.
2. Just because it's horrible for others, doesn't mean it will be for you. Like I said, everybody is different.
3. Don't quit cold turkey like I did. Even though I didn't have a big problem with it, you may. I did it because I was at my wit's end and felt I was having side effects from the meRAB.

I hope to be reporting back in a week or two feeling the same way. I'm crossing my fingers and toes hoping I'm on the right track.
 
the burning stomach feels like there is a hot iron over the center area of the stomach. I'm also getting bloating along with it. I assume it is from hyper-acid secretion
 
I've been off PPIs for about 2 months. No miracle cure, but I don't feel any worse than I did on the drugs.
 
I don't have a burning stomach but my abdominal area does seem off. I don't feel sick or anything. Just maybe like a bloated feeling without the bloat, if that makes sense. But I don't have any heartburn. Maybe there is a lot of acid but it's not refluxing, which is a good thing. I'm hoping that when it calms down I'll feel better in the abdominal area. I also have muscle aches, spasms and pains but that is from my anxiety level, which has been way high lately. They should subside once I calmed down.
 
I tried Aloe Vera juice and it didn't work for me. I seem to be doing well with the regimen my ND has me on.
 
so I'm not sure of your exact timeline. You quit on Aug 6 cold turkey taking Zantac for some time? What rebound did you experience? I got a terrible burning stomach last time I tried.
 
When I quit I had problems for about a week - popped a lot of Tums to control it. The rebound went away and I was soon in the same state I started in.

Now to try to get better...
 
Flyerfan,

How is your melatonin treatment going ? I'm curious about it and thinking about trying it out.
 
Sorry. I wasn't really clear on that, was I? My last PPI was on August 3...stopped them cold turkey, I didn't wean off them. I started taking Zantac on Aug 5 and very quickly went from 150 mg 2x/day to 75 mg 2x/day to nothing...all in 10 days. I've been off acid reducers of any kind for 15 days.

Can you describe what the burning stomach feels like? Is it like nausea, indigestion? I've read many posters who've had this but I have not experienced anything like that.

It just seems like 7 days ago I stopped getting the frequent burning in sternum to throat. I get it very mild now.
 
Sorry, it took so long for the reply...been on vacation :)

I truly believe the melatonin is working. I am into my 3rd month being ppi-free and on 6mg melatonin each night and I think it has helped to strengthen the LES. Not entirely however, because I still notice I get burning in my stomach at times and I do feel very minor irritation in my throat area but it don't last for long. I have resorted to Zantac 2 or 3 times in the past 2 months when I had a lot of the stomach burning. Other than that, I've been using the DGL.

I still have some reflux at times, especially when stressed, but sometimes for no reason at all and it's not related to any particular food. On vacation, I ate more sugar and carbs than I was used to. However, I had no flare-ups of reflux that were anything different to what I was getting on my strict low-carb, low-sugar diet. I just think that my system is still working it's way back to normal. I get a few days in a row where I have not much of anything and then a day or two where I feel it more. Not anything a little DGL wouldn't fix.

I believe the melatonin is helping but it is not a quick fix. I don't know how much longer I will be on them. I'll see as time goes on.

Best of luck to you.
 
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