FDA approves Truvada, first pill to prevent HIV infections - Boston.com

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By Deborah Kotz, Globe Staff
On Monday, the US Food and Drug Administration approved Truvada, the first medication intended to prevent HIV infections in people having sex with infected individuals.
When taken daily, Truvada (emtricitabine/tenofovir disoproxil fumarate) reduced the risk of HIV infection by 42 percent compared with a placebo. That was in a clinical trial where HIV-negative individuals had unprotected sex with multiple partners, including some HIV carriers, according to the FDA. Another trial involving heterosexual couples where one partner was infected -- and condoms were used routinely -- found that Truvada reduced the risk of infections by 75 percent.

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