Other thoughts...
They could take common viewer complaints and basically spit in the faces of those people by taking those complaints and doing entire segments based on them, but increasing it tenfold. For example, if someone complained about too much Herbert, they could do a sequence containing nothing but Herbert. Sort of a "day in the life" sort of thing. Even funnier is if they took the common complaint that jokes and cutaways are too long and either do a sequence where nothing lasts longer than 15 seconds or do a sequence that's just one verrrrrrry looooong, boooorrrring cutaway, such as this one I thought up a few weeks ago:
(Peter is pouring lighter fluid on an already lit barbeque)
Lois: Peter, don't you think that's enough lighter fluid?
Peter: Lois, when I'm done here these will be the best damn hot dogs you've ever tasted:
Stewie: Ugh, I remember the last time I added fuel to the fire.
(cut to Stewie in his bedroom. He's wearing worker's overalls and he's just finished painting the walls of his room)
Stewie: Now then. All finished.
(Stewie sits down and literally starts to watch the paint dry. Seriously. He just sits there for the duration of the sequence. He coughs a couple of times, maybe yawns once or twice, but otherwise just sits there watching the paint dry. Eventually, after about 7 or so minutes, he gets up and begins to walk away.)
Stewie: All right. Now to see what the internet thinks about that.