It depends, it'd be another cliche for Seths list if he spoofed anime. If he did he should spoof the common poor animation, the characters that usually walk\run in place at a distance, the cliche old man gag, the fact that most newer animes have unneccasary logic behind each thing thus an enemy will freely shout out loud lectures to his\her other enemy in a fight, and the fact that despite animes being "realistic" most animes don't portay driving physics correctly, its nearly impossible to make a turn, stop for a second, and immediatly return to full speed. I'm okay wuith anime but I'm highly critical of animation too, I spare minimum to any.
