i work as a flight attendant right now and 2yr olds really do drive us mad when the parents aren't controlling their child! stop expecting flight attendants to have spare diapers, formula, medicine or toys. take your kid to the restroom before you board. leave the dry cereal and legos at home and bring snacks and toys for your kids that won't make a horrible mess.
but san diego california is a GREAT place to go!! especially during the summer. check out seaport village, the zoo, balboa park (free on tuesdays), coronado, and the beautiful many many beaches and great dining!!!
but take a plane and rent out a car...haha