It would't be the first time an animated film has been remade. Remember Disney's live action 101 Dalmations? They also have a live action version of Beauty & The Beast in the works, based off the Broadway show. That would be a first. A live action movie based off a Broadway show based off an animated movie.
About Yellow Submarine, I too fear if Disney is planning to use the Jonas Brothers, because it really sounds like something they would do. Zemeckis, though, may not allow it, though. A Roger Rabbit sequel has been in talks for several years, but it has yet to actually get produced.