Characters with good chemistry togother

Joseph and Hank Hill from King Of The Hill are a great pair together. Joseph is the awkward teen with no social skills and Hank is the uptight "normal" guy. It always leads to the most interesting interactions on the show.

Much like Bobby and Bill. This is definitely the weirdest duo on the show, as they seem to act COMPLETELY different towards each other than anyone else. I always have to watch episodes with these two paired together more than once just to try to understand their chemistry as characters together.

KOTH is the best with character chemistry.
 
Prime and Megatron from G1,BW and BM.

Xavier and Magneto: X-men TAS and EVO

Superman & Lutor: Superman TAS

Batman and Rase al Ghoul: Batman TAS

Reed and Doom: FF 90`s and the current one

Flash and GL: JL

Rowen and Kayrau:RW
 
you call this a "god chemistry" thread,yet you fail to mention mindy and buttons,slappy and skippy,or rita and runt? those are my picks simply for the following.

slappy and skippy-any animaniacs fan out there will tell you that "who's on stage" was one of their best skits ever.

rita and runt-yeah,it's basicly following the smart/dumb formula,it's all good. (OT,bernadette peters has an awesome voice)

mindy and buttons-how they stayed fresh but still used the same structure for their shorts I'll never know.
 
Well I never liked Mindy & Buttons. That was always one of my least favorite segments in Animaniacs. I would typically change the channel whenever M&B came on, but I agree with you about R&R and especially S&S.
 
yeah,I never liked them either,it was just the same plot every time,but the other two segments were possibly the best in the series(including the warners). also,another combination I found was sonic and tails from basicly any sonic cartoon the twosome appeared in.
 
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