Question for cell bio - genetics related questions: answer any if you can please preparing for dcats..
IS statement true or false. If false, explain why.
1. Primase is needed to initiate DNA replication on both the leading strand and the lagging strand.
2. The Sliding clamp is loaded once on each DNA strand, where it remains associated until replication is complete.
3. Telomerase is a DNA Polymerase that carries its own RNA molecule to use as a primer at the end of the lagging strand.
4. Primase requires a proofreading function that ensures that there are no errors in the RNA primers used for DNA replication.
5. A molecule of BACTERIAL DNA introduced into a yeast cell is imported into the nucleus but fails to replicate. Which protein or protein complex is responsible for this?
Primase, Helicase, DNA polymerase or Initiator proteins.
6. Sometimes chemical damage to DNA can occur just before DNA replication begins, not giving the repair system enough time to correct the error before the DNA is duplicated. This gives rise to mutation. If the adenosine in the sequence TCAT is depurinated and not repaired, which of the following is the point mutation you would observe after this segment undergoes two rounds of DNA replication?
a. TCGT, b. TAT c. TCT d. TGTT
Which of the choices below correctly indicates the gene combination from the replication products of the maternal chromosome?
a. AB and aB b. ab and Ab C. AB and Ab D. aB and ab
In addition to the repair of double-stranded DNA breaks, homologous recombination is a mechanism for generating genetic diversity by swapping segments of parental chromosomes. During which process does swapping occur?
A. DNA REPLICATION B. DNA REPAIR C. MEIOSIS AND D. TRANSPOSITION.
Homologous recombination is an important mechanism in which organisms use a back up copy of the DNA as a template to fix double-stranded breaks without loss of genetic information. Which of the following is not necessary for homologous recombination to occur?
A. 3' DNA strand overhangs B. 5' DNA strand overhangs C. Long stretch of sequence similarity D. Nucleases
IS statement true or false. If false, explain why.
1. Primase is needed to initiate DNA replication on both the leading strand and the lagging strand.
2. The Sliding clamp is loaded once on each DNA strand, where it remains associated until replication is complete.
3. Telomerase is a DNA Polymerase that carries its own RNA molecule to use as a primer at the end of the lagging strand.
4. Primase requires a proofreading function that ensures that there are no errors in the RNA primers used for DNA replication.
5. A molecule of BACTERIAL DNA introduced into a yeast cell is imported into the nucleus but fails to replicate. Which protein or protein complex is responsible for this?
Primase, Helicase, DNA polymerase or Initiator proteins.
6. Sometimes chemical damage to DNA can occur just before DNA replication begins, not giving the repair system enough time to correct the error before the DNA is duplicated. This gives rise to mutation. If the adenosine in the sequence TCAT is depurinated and not repaired, which of the following is the point mutation you would observe after this segment undergoes two rounds of DNA replication?
a. TCGT, b. TAT c. TCT d. TGTT
Which of the choices below correctly indicates the gene combination from the replication products of the maternal chromosome?
a. AB and aB b. ab and Ab C. AB and Ab D. aB and ab
In addition to the repair of double-stranded DNA breaks, homologous recombination is a mechanism for generating genetic diversity by swapping segments of parental chromosomes. During which process does swapping occur?
A. DNA REPLICATION B. DNA REPAIR C. MEIOSIS AND D. TRANSPOSITION.
Homologous recombination is an important mechanism in which organisms use a back up copy of the DNA as a template to fix double-stranded breaks without loss of genetic information. Which of the following is not necessary for homologous recombination to occur?
A. 3' DNA strand overhangs B. 5' DNA strand overhangs C. Long stretch of sequence similarity D. Nucleases