Well, I can imagine The Jetsons. The Flinstones live-action movie was pretty good. But then again, now-a-days, they'd probably strive so hard to make it feel so "realistic" rather than let loose and be like "Whatever, it's a cartoon, lets make the props cartoony." like in the Flinstones movie, it'd probably depress a lot of people.
I think it's more interesting to see real life pictures of cartoon characters rather than films.
Like, I wouldn't mind seeing a Johnny Bravo photo shoot to see how they would look in real life, or Courage the Cowardly Dog, or Fairly Oddparents as opposed to an actual film.
Like that South Park drawing that showed the boys how they would look in real-life, only with actual people, not drawings.