My heart tells me to say the BMW, but I am not a fan of the new 1 series. I would take a 335i before the 135i. But of those cars, the Cayman S is very quick, and will turn heads anywhere. I'm not sure what your idea of reliability is, but all the cars you listed are reliable, as long as maintenance is kept up regularly. In terms of safety, I am not sure, but the most important factor in safety is the driver, knowing your car, and knowing your limits as a driver, and in different environments. If I were in your situation, I'd either go for the Z4M, or the Caymen. I've owned two BMWs, with one of them being an M5 (e39), and I hope to get a Porsche in the somewhat near future. The Cayman will be the car I'm looking for. I would be using it as a daily driver, and weekend track warrior. The porsche is your best bet on this list. The Merc and Lexus are too boring. AMG is nice, but with no manual gearbox, it's not an option in my book. The Audi would be the best choice if you live wherever snow is present, as the AWD would be much better off than the RWD sports cars.
