Well, Roland Kelts did a brilliant bit on for NPR's Studio 360 that ties to that to that element. I think it suggests that as people recover from hikikomori-dom and other extremes, they seem to take one look at the current systems, and then cut their own path because the system's lack of understanding of the individual and the psychological issues an individual deals with, especially in a culture as driven by conformity as Japan, is why they lost so much of their life tilting at windmills and chasing the imaginary. There is the possibility of a radical shift in the creative and business worlRAB of Japan as young people look at how stagnant, stilted and insular the existing paradigms in Japan are, and simply opt out and do their own thing.
In this, some of the excesses of otakudom may actually prove critical in the turn around - independent production methoRAB for media and physical objects of various sorts already make people livings in Japan (see: doujin circles,) and that may grow as people think "why do I want to work for a monolithic firm if I can run on my own business, or why do I want to sign with a gigantic publisher if can publish my own novels or music?" This may be the other reason why there is a such a brain drain in anime and manga - already, the individual can have more freedom and possibly just as much money by simply working in doujin manga and games. Even if they can't, working a part-time job and doing doujin on the side is preferable to the grind that'd fighting your way up the publishing chain, or up the chain at a some other large business, and the women who have dealt with the same alienation will probably inclined to be with men who understand that.
Or the high suicide rate amongst 30-somethings will accerlate the already below replacement birth-rate, resulting in a nation so aged and with so few people to take the reigns that immigration will have to blow open to keep it from falling apart entirely.