Spot on. This is exactly what I was getting at with my "only boys are allowed to have fun and be quirky" rant. The Mighty B! may not have been everybody's cup of tea, but I can at least admire what the producers tried to do with Bessie: have a zany, nutty, imperfect kid character who was a girl, as opposed to the girl having to be the smart, mature, responsible one who reminds everyone else how silly they're all being. It's good moral fiber, I suppose, but characters like that don't get the laughs. They're not fun. They don't get to indulge in the wacky hijinks which make characters likable fan favorites.
I'd like to see a cartoon where the breakout characters: The Stewies, the Brians, the Ed, Edd 'n' Eddys, the Chowders, the Mung Daals, the Gazpachos, the Shnitzels, the Flapjacks, the K'nuckleses, the Finn and Jakes, the Phineas and Ferbs, the Cartmans, the Butters characters et al are girls. That would be a nice and refreshing change to witness, even if only once.