Presuming that Palin has had time to appoint a new Vice President, under the 25th Amendment that appointee would have to be confirmed by majorities of both houses of Congress, which would be under Democratic control. You think either house would confirm any wacko SHE would appoint? Therefore, it would then go to Speaker Nancy Pelosi.
Then, with her appointee for Vice President... Barack Obama, perhaps?... and Speaker Steny Hoyer and Majority Leader Harry Reid running things, we'd get REAL change!