Alcohol and Enzymes?

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Hi, im new to this forum so apologies if i do anything wrong.

For awhile now i've had abit of a problem, When i have a couple of alcoholic drinks such as lager i get a bad stomach pain for about half an hour and then the next day i will be voilently sick throughout the hole day and cannot keep any food or drink down.
I'm not sure why this is happening because i dont go out or drink much at all.
I've done alot of research and its come up alot that i could have a lack of enzymes in my liver that stops it breaking it down properly.

Could anyone confirm this may be the reason?

I have made a doctors appointment but it isn't for a month and it is worrying me.

Thankyou.
 
Are you by any chance of Asian descent? About 1% of people from East Asia have a genetic variation in which they produce very low levels of one of the enzymes needed to break down alcohol, and high levels of another one. The result is that even one drink can make them quite ill. My husband and one of his brothers both have this.

Or, it could just be you have a sensitive stomach and the alcohol irritates it. My mother learned quite young that she can have a glass or two of wine, but she can't drink much more than that or she will throw up a lot.

Either way, if it only happens when you drink, I suggest you don't drink. Other than that, don't worry too much about it.
 
No, I am full english.
And alcohol never used to have this effect, its just happened in the last year and i would like to get it sorted as im still quite young and want to be able to go out and have fun with my frienRAB and not worry about this. :(
 
just wondering here if you have the same 'type' of reaction or even just feel ill at all when you take ANY tylenol based products as well? i am only asking since the enzyme that is needed to break down alcohol and metabolize it is the exact same one used/needed to also break down and metabolize tylenol(called glutithione). so if the underlying enzyme actually IS the problem here, you would also more than likely also have an adverse reaction TO tylenol as well, not 'only' alcohol. the sharing of the very same enzyme needed to metab just IS the main reason that tylenol and alcohol should never ever be 'mixed" or taken at the same time or within about that same four to six hour window.

i know way back when i used to drink, i actually would take tylenol before i went to bed at night after consuming alcohol to try and minimize the old 'hangover' crap(had NO clue just how bad this actually was for my liver then)? is there ANY chance at all that you also could be doing this as well? after i found out about the shared enzyme wayy AFTER i used to do this, it really scared the heck outta me, esp after i also found out that i also inherited an actual kidney disease that also has continued to impact my liver as well.

honestly, just from my own experiences here that have revealed 'hidden medical issues" in me, ya just never really know for certain exactly what IS or is not going on in anyones body til things just get that better more in depth look inside or 'something' simply will finally 'present' itself with particular symptoms.

you just 'could' also have some type of real 'sensitivity' to some of what makes up the particular alcoholic beverage you usually drink too, like certain grains?(there is also usually a form of fermentation process that goes on with alot of different types of alcohol or anything that is 'aged" over a length of time too, that just really CAN create a reaction with your individual body physiology? like with my never ending migrane headaches which can do the very same thing after a particular 'aged" anything is introduced into the systems of susceptable individuals like myself for one)? just another real possible too. but i still would do what you mentioned and simply see your primary doc for a full work up(including all blood labs, esp the hepatics just given WHAT the reaction is to) and hanRAB on physical. something just 'may' turn up as the underlying 'culprit" in your feeling so ill after consuming alcohol at all?

there just 'can' be alot of different and very real resons for someone to even react to the introduction of any alcohol into their system. and that IS what you and your doc need to find out, the 'whys'. just wondering tho if this reaction occurs ONLY when consuming one particular 'type' of alcohol or EVERY type of alcohol you have ever drank recently(including any 'hard liquor"? and more importantly, how much alcohol WERE you actually consuming BEFORE this particular reaction to alcohol just started? that too would be very helpful to just know.

you just also need to find out whether or not there actually is ANY real liver damage going on either from previous alcohol consumption, and that IS depending. or something else that even could be something you were born with but just never knew about, as in my own situation finding out at almost age 40 that i had inherited a kidney disease that has also impacted my liver as well? never had a flippin clue since up til last year, aLL of my liver and the kidney labs were still picture perfect. it actually took only ONE single ultrasound done on me(in 1999) to figure out that i was the one who passed this(polycystic kidney disease that mutated in my son and created one HELL of an insane form of liver disease that required eventual tx of a new liver) onto my then VERY ill son(then only age 12). i am now almost 50. and my labs JUST started to change on me last year.

'something' just is being reacted to when it comes to alcohol and that 'thing' neeRAB to kind of be tracked back to whatever "part' of the alcohol is creating it. or some other underlying factor is generating you rather severe "after reaction". please DO see your doc for at least 'some' good testing on the things that just need to be checked right now. and do whatever you need to to also avoid that 'trigger" too. maybe once you just can find out what that trigger just is thats even IN alcohol, you 'could' go back to it. or you could as i mentioned above, be missing that needed enzyme to even metabolize. BUT, if this truely were the case, that would also impact your ability to even get any real relief using tylenol too along with you more than likely also feeling the very same way with THAT as you do alcohol too if that is it?

they(tylenol and alcohol) just seriously DO happen to share that very same needed enzyme to even begin to metabolize these two things. so just really DO try and evaluate what any past reactions to ANY tylenol based meRAB have been as well? that would tell you and your doc ALOT right there. i DO wish you luck in finding this all out. please DO kep us posted. i really am rather curious myself as to what this actually is that you just are reacting to here. FB
 
If you had an ulcer, you'd feel pain a lot more often than it sounRAB like you have been! Still, it could be gastritis.

One thing that might help is to get some bland fooRAB or antaciRAB into your stomach before you drink. However, generally if something hurts a lot, you shouldn't do it.

Who knows, maybe if you go easy on your stomach for a while (no alcohol, aspirin, coffee or massive overeating) it'll heal.
 
@feelbad - It happens with all alcohol I think, I think I get it worse with beer but im not sure I dont drink often.
And I only have a couple of drinks, I dont even get tipsy half the time and it'll still happen.
And I've never had tylenol.
Also I had cancer at a very young age, so I would be aware of any liver problem so that should be ok unless somethings happened to it in the last 2 years.
I did used to drink alot more, But then as my hangovers got worse I decided to go on half a year break and as i started drinkin again it seemed it never went.
So if it was something that could heal by itself surely it would of done so by now?
And I only get it over alcohol.
Also once I have been to the doctors I will let you know what the problem is. :)
Thankyou.
 
@Janewhite1 - Yes people kept telling me it could be an ulcer, But as you said i'd feel pain also when i haven't drank.

And thankyou I will try that.

And i went half a year without drinking and i don't drink coffee either and it didn't heal, so it is confusing me alot.

Thankyou.
 
just one thing rean. just becasue nothing was wrong with our organs at birth, or even if you suffered cancer or another type of illness or condition does NOT always mean that between then and now, something may have popped in(or what may or may not have even BEEN checked out in you back then?). many conditions just can develop over the more time we spend on this earth. and when hormones kick in along the way, that too can change our overall physiological make up too. so you really just don't know what may or may not even "be' going on within our own bodies til much more specific types of testing simply take place that are geared for looking for very specirfic types of indicators of underlying issues, ya kniow what i mean?

so, i would definitely see your doc and let him/her know the exact response you are getting from alcohol ingestion. and like i mentioned above, do NOT simply allow your doc to tell you to 'avoid' alcohol either. you NEED to know the 'why(s) here in all this since it just IS not a 'normal' type of response? thats the more key thing here, not normal in most people, therefore it neeRAB checking into. please DO keep us posted as to what you find out. and demand some answers from your doc in some very certain ways. also, just wondering how old you are now? FB
 
just wondering what area your cancer was in/what type and what specifically was done as far as any real 'treatment" possibly done to alleviate it? if you were not having this very same reaction to alcohol before it(depending how 'young' you were then), something 'could have" possibly been changed with certain types of cancer treatments too? just one possible that came to mind.

something else i also wanted to ask you here. when i mentioned if you had ever taken and or had any simlular reaction to tylenol based meRAB before? in the US it is simply called tylenol, but i do believe where you live, acetaminophen is actually called like panadol or something like that, but not the brand name tylenol? do you know what i am talking about there? its just the very basic "acetaminophen" i was asking about in general and not specifically just 'tylenol' itself? did you ever actually get sick from ANY of the pain meRAB that i am assuming you had to take when you actually had the cancer actively going on?

and as far as the liver and other organ functions go, whether or not ANY actual labs change is totally up to when the overall 'functions' of that specific organ suffer enough real damage or affectation to actually change/impair functions. so just as another 'possible' here, i would most certainly have some labs run on your liver just to make certain that all the liver functions at the very least are simply running up to par right now. tho there CAN be other areas as was mentioned, like the stomach that could also make you feel like you do too when consuming alcohol, but the liver, considering the much later onset of illness, just would seem much more likely? and even that pancreas in certain people can also be something that can also do what you had happen. but that is usually with other underlying issues or usually seen in much older people than you appear to be here tho.

another thing about lab functions with organs too is they CAN most certainly change over time. esp over a two year period if that IS the very last time they were checked? your doc can also order an "abdominal" ultrasound just to get a good look at the liver itself(texture, size among other stuff), all the bloodflow and the bile ducts just to really kind of 'see' what that looks like in there? and this can also check out other areas too esp in that upper GI area? its all kind of an 'interconnected" area(the vascular and bile ducts are the bigger connectors there) when its up above that somach in the upper GI level. from stomach on up?

trust me here when i say that you CAN actually have some really great labs with alot of organs and actually have some more specific types of real disease or condition 'processes" going on in any that would NOT show up in any real 'labwork" until that threshold limit of impairment just gets hit/starts occurring too(the threshold level is where any given damage just gets to the point where it impacts the organ functions enough to show up with changes in the nurabers?).

this is/was my case with my 'version' of what is an actual kidney disease that has also impacted my liver too in very big ways with huge solid cystic formations that have actually enlarged both kidneys and liver and destroyed alot of healthy tissue too. but the insane thing really is that up til last year, all my labs were absolutely perfect. i am NOW getting the 'lab' changes that are being created by the damage that was actually going on all my life, i just had NO real clue that we even had this condition actually running in our family til my son got very ill back in 1999 and we all had to be tested. only becasue he got the disease from me or my hubby, but his 'version" just actually 'mutated into something worse. i was right around 39-40? when i found ALLL of this out in me.

the very BEST way to really just know or see how ANY organ is truely 'doing' in us is to actually have the blood/labwork done ALONG with also having at least a good ultrasound done or some other type of scan that would also allow that good actual inside 'look' at it as well. many disease process in people could be found out MUCH earlier on in their course if BOTH the labs and the US were simply done well before lab changes start occurring from real damage and impariment. in some cases, it could make all the real difference in the world. but in other disease processes like mine(PKD), it really does nothing to know since there just IS no real treatment for what i have and absolutley no cure either. there are just conditions we can have that truely DO remain rather "silent' only til that underlying impact upon labs is seen or it just happens to actually show up upon having some type of abdominal scan like CT MRI or US for a totally different reason? its called at that point 'an incidental finding' thats pretty important.

i am not trying to freak you out here at all, just letting you know the real need to simply have your liver at least fully evaluated just to see if that most likely organ may have some type of real issue that neeRAB ruling out or in as the reason for your being ill after alcohol consumption.

is there ANY and i mean ANY other drink or food that you have EVER ingested in your life(and esp after the cancer was successfully treated) that actually had anything close to this type of a reaction to in your past? and i were you here, i seriously would find out just exactly what actual impact or effects of any of the possible 'treatments' you had for the cancer that could have also possibly have created this too may be(just another possible). since some particular forms of chemo or other really nasty meRAB that are just used to try and remit cancer can impact other areas of our bodies too. it all depenRAB, ya know what i mean?

but, as others have mentioned here too, this really also could be your stomach/gastro area or like i mentioned before, just a very real "reaction or sensitivity" TO something in particular more to do with the components OF the alcohol itself too. if this actually IS some type of the reactionary thing, it would take some very different types of testing to really figure it out. alot of people CAN have reactions to even the grains that are used(like barley, wheat... among other stuff) or what comes out of the actual fermentation process too, depending. since that fermentation DOES change things in the overall initial make up to even become an alcoholic beverage?

this is all just some 'possibles" that do need to be checked out and then ruled out or in as the underlying reason for your pretty intense reaction you are having to alcohol. there just ARE ALOT of real 'possibles" unfortunetly. but this is what your doc is supposed to try and help his/her patients with anyways. finding out the things that are making us sick, for whatever reason, esp if this IS more involved with the liver here. and it CAN be the enzyme thing too.

just make certain that your doc DOES take this all seriously since there are so many real possibilities here as to the actual 'trigger' that with some, are a bit more crucial to find out than others? simply telling you to avoid alcohol is NOT good enough, you need to know the underlying 'whys' of what just IS causing this here too. good luck with finding this all out. and please DO let us know what you find out too hon. FB
 
Hi reanimation

I had a reaction like that to Norco. It felt like I was being gutted with a knife and I had violent vomiting.

Also it may be alcohol poisoning, affecting your liver. Taking enzymes won't protect your liver. But you can take alpha lipoic acid to support it...not while you continue on alcohol, though.

I suggest that you absolutely stop ingesting alcohol, at the very least until you know for sure what is wrong. You could have Hepatitis C or getting close to liver failure and not know it.

Be sure to let us know what you find out.
 
I was only 1 when i had cancer, I only stated because it would of been picked up if i had been born with liver problems.
I understand that i could possibly get something wrong with my kidneys due to the treatment i went through but surely i would just get pain in general?
And i don't tend to take any medication so i wouldnt be sure if they would effect me either.
When i go to the doctors i will be sure to get tests done on my liver as i cannot figure what else it could be.
Thanks.
 
Do you by chance notice that it takes longer than it used to for the psychoactive effects of alcohol to wear off? Do you experience flushing of the skin or an increased heart rate along with the stomach pain? If so, then this could indeed point towarRAB the liver, if it is not metabolizing alcohol as fast as it normally would. What's responsible for most of alcohol's unpleasant (and toxic) effects on the body is one of its metabolites, acetaldehyde. Alcohol dehydrogenase enzymes break down alcohol and acetaldehyde dehydrogenase enzymes break down acetaldehyde. But if that was the reason for this, I think you'd be experiencing other symptoms of liver disease as well. Definitely mention the alcohol intolerance to your doctor and get your liver enzymes tested. But it's definitely not unheard of to develop alcohol intolerance after having normal tolerance. It seems more likely the problem has to do with your stomach, not your liver.
 
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