You'll have to change both. The AX-15 is a medium duty transmission and can't handle the V-8 nor can it bolt up. The challenges are going to be the deepness of your pockets (expect to spend in the thousands), and the time you have to make it happen (expect months of down time). You may also have to swap out the rear axle for a stronger one so you don't break the shafts. Powerful swap, but it will unbalance your rig. Go for the smaller V-8 or better yet: rebuild your current engine into a stroker. MUCH less work and you get a huge boost of power all the same.
Good luck!