Not a noticeable difference in knockdown, but there COULD be a difference in accuracy, depends on the rifle. I have a 204 Ruger that won't group ANY 40 grain bullets under 1 1/2", but it will group factory 32 grain ammo in less than 3/8". I can't explain it, but some guns shoot different ammo better. Buy a box of each and see how they group in your gun. It could be very similar, or one could group considerable better.