Then proberbly Beaches as My best friend wasn't very well at the time and i couldn't imagine living witout her.
But she's just got married and she's expecting her second baby so everythings fine now.
ET, The Green Mile, Shawshank, Schindlers List, the very end of Star Trek 2 with Spock's sacrifice and funeral, Gladiator, oh many many more. I love a film that makes you cry, somehow it makes the film so much better.
Not sure about first but recently the end of Cast Away was emotional. Tom Hanks goes through the hell of suffering on an island for four years and returns home only to find his wife has now re-married and his old life is shattered. A very bleak film not a bit like Robinson Crusoe.