well, you'll certainly need a larger frame. i'm 6'0" and i was fitted with a 58cm Serotta. for 6'5", you'll need at least a 60-62cm frame (unless you have really short legs!). going to your local bicycle center with qualified bike fit specialists will ensure you get a bike that fits you properly. of course it will cost you a little bit more but your back and shoulders will thank you down the road. most road bikes today have integrated brake/shift levers. if you're comfortable with finding the right size you can go through internet/mail order and find some really good deals. even on ebay, if you know what you're looking for. some of the ebay sellers will take your sizes/measurements and get a bike that will be a pretty good fit. you may also want to take a look into a "hybrid" bike. it's frame is designed about 1/2 way between a dedicated road bike and a mountain bike. if you're not looking to race, it's a nice mix. just remember your contact points, get good shoes, good shorts and a decent pair of gloves and you're riding will be MUCH more comfortable. (and please wear a helmet!)