Y
yupitsmela
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A poison added to an in vitro translation mixture containing mRNA molecules with the
sequence 5′-AUGAAAAAAAAAAAAUAA-3′ has the following effect: the only product
made is a Met-Lys dipeptide that remains attached to the ribosome. What is the most
likely way in which the poison acts to inhibit protein synthesis?
(a) It inhibits binding of the small subunit of the ribosome to mRNA.
(b) It inhibits peptidyl transferase activity.
(c) It inhibits movement of the small subunit relative to the large subunit.
(d) It inhibits release factor.
(e) It mimics release factor.
sequence 5′-AUGAAAAAAAAAAAAUAA-3′ has the following effect: the only product
made is a Met-Lys dipeptide that remains attached to the ribosome. What is the most
likely way in which the poison acts to inhibit protein synthesis?
(a) It inhibits binding of the small subunit of the ribosome to mRNA.
(b) It inhibits peptidyl transferase activity.
(c) It inhibits movement of the small subunit relative to the large subunit.
(d) It inhibits release factor.
(e) It mimics release factor.