I have a few questions so answer whichever you can!
1. In propanol, cholesterol is 2.7 times more soluble at 43°C than at 20°C. If a saturated propanol solution is prepared at 43°C , what proportion of the cholesterol will
crystallize upon cooling to 20°C?
2. What is the configuration at position 3 of the cholesterol molecule? Axial or equatorial?
R or S? Draw the cholesterol isomer with the opposite configuration at position 3. Be
sure to show the absolute stereochemistry of all chiral centres.
3. Bilirubin is a bile pigment commonly found with cholesterol in gallstones. Biliverdin is
another bile pigment also commonly present in gallstones. Draw its diethyl ester. What
is the difference between bilirubin and biliverdin?
1. In propanol, cholesterol is 2.7 times more soluble at 43°C than at 20°C. If a saturated propanol solution is prepared at 43°C , what proportion of the cholesterol will
crystallize upon cooling to 20°C?
2. What is the configuration at position 3 of the cholesterol molecule? Axial or equatorial?
R or S? Draw the cholesterol isomer with the opposite configuration at position 3. Be
sure to show the absolute stereochemistry of all chiral centres.
3. Bilirubin is a bile pigment commonly found with cholesterol in gallstones. Biliverdin is
another bile pigment also commonly present in gallstones. Draw its diethyl ester. What
is the difference between bilirubin and biliverdin?