paradox reaction to benzodiazepines, permanent damage?

anaeli

New member
Preface: My grandmother is 75, healthy, lives independently, and has a comparatively active lifestyle and has never had significant health issues, although she is deaf but had a successful cochlear implant.

My grandmother is currently in the hospital and her doctors are stumped. We can not figure out what is going on. A few years ago a doctor prescribed her Xanax. She apparently had a paradox reaction and instead of becoming sedate or having anxiety relieved, she became aggressive and agitated and unable to be controlled.

That particular doctor said she could no longer have benzodiazepines. She returned to normal after a week, but close family members noted her personality never reoriented itself completely.

Now, years later, a new doctor in a new (very rural) area added a diuretic to her blood pressure medicine (lisinopril). Her sodium bottomed out soon after and she went into a dementia state. In order to sedate her, the doctor gave her atavan, perhaps he didn't know that she could not take benzodiazepines. My other family members didn't make the connection. She went absolutely bezerk again and the doctor continued to administer atavan up to 3mg per day. She stopped sleeping and she remained in a constant state of agitated psychosis. He ran a lot of tests on her but couldn't find anything physically wrong, while continuing to administer atavan, and he suggested we admit her to a psychiatric ward.

I'm going to refrain from making emotionally charged statements here, but personally, I have strong feelings about how this doctor handled my grandmother's case.

My aunts and uncles transferred her, against that doctor's will, to a big city hospital where they immediately abstained her from all drugs, except for blood pressure medicine (lisinopril without the diuretic.)

She has been here 7 days without atavan. She will not sleep on her own. After two days with no sleep the doctor gave her haldol and later zyprexia and melatonin. With these medicines she sometimes sleeps for no more than 4 hours. Last night she only slept two hours. When she wakes up she is highly agitated and babbles compulsively about random things. She usually has 3-4 topics that she anxiously cycles through. I can calm her down about 1 hour after waking up, and she remains somewhat calm for the rest of the day.

This is very stressful on myself and the rest of my family members. She's traumatized some of my uncles by telling them their adopted and that she doesn't want them around, etc etc.

The neurologist, doctors, and psychologists can not figure out why she isn't sleeping on her own and why she is consistently lingering in this state of borderline psychosis. I don't feel that it is a true psychosis, however.

They wanted to do an fMRI, but her cochlear implant restricts her from the scan.

Please help!
 
I am so sorry this happened to your grandmother (or anyone!). Before anything is prescribed, the medical profession should always make sure they know of any known allergies or sensitivities. We cannot trust them to do this...we have to make sure ouselves. The elderly need an advocate to look after their concerns. I am not against doctors in any way, but if the number of dangerous mistakes were actually known we would be scared to use them. We need to research every drug ourselves before we decide to take any.

I would suggest that you see if you can get her seen by a wholistic-medical doctor, meaning one that studied more than just medicine and knows how to detox drugs from the body, ie brain and liver. She seems to be poisoned. I am very sensitive to drugs, myself and can not take hardly anything without a reaction.

I wonder if there are heavy metals in something she was given. (I hope you don't listen to the colon detox info out there...her colon doesn't need 'detox'.)

I would demand she be checked by a poison specialist.

I would make sure that she can NOT take any type of benzodiazepine is written on top in red on every medical information on her.

I personally would not allow her to be out of your control and oversight. There is no reason for anyone to get upset over what she does or says, since she clearly is not in her right mind. It's not her fault she isn't connected to reality right now...you guys can sort that stuff out later.

I also would seek a malpractice attorney to find out her rights, since her medical needs have soared. This mistreatment is disgraceful. Throwing drugs at problems is irresponsible.


So...I am mad right there with you!
Please keep us updated!

You might benefit from reading Brain-Disabling Effects of Benzodiazepines, by Breggin M.D.
 
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