Dec. 10, 2013 — An experimental compound synthesized and developed by scientists from the Florida campus of The Scripps Research Institute (TSRI) has the capacity to significantly reduce joint inflammation in animal models of rheumatoid arthritis, an autoimmune disease that affects more than two million Americans.
The study was published recently online ahead of print by the journal Arthritis & Rheumatism.
The study showed the compound, known as SR2211, blocked development of virtually all symptoms of rheumatoid arthritis in mice within the first eight to ten days of treatment. The mice also showed significantly reduced bone and cartilage erosion compared to animals that did not receive treatment.
The experimental compound targets the nuclear receptor ROR
The study was published recently online ahead of print by the journal Arthritis & Rheumatism.
The study showed the compound, known as SR2211, blocked development of virtually all symptoms of rheumatoid arthritis in mice within the first eight to ten days of treatment. The mice also showed significantly reduced bone and cartilage erosion compared to animals that did not receive treatment.
The experimental compound targets the nuclear receptor ROR