If it's anything like Spain, expect the level of driving to be 5 times higher than in the US. Yes, they drive fast (very fast!), but way better than on this side of the pond. Every traffic light is a drag race, and every round-a-bout is a test of one's handling capabilities. It also takes lots of money and weeks of training to get a license in Italy/Spain.
Even better, there is a level of respect to motorcyclist that you won't find anywhere. We rode into Barcelona through a 5 lane tunnel at rush hour once. As we lane split our way through, the traffic parted for us like Moses and the Red Sea. Absolutely amazing.
I talked to a few people about it, and I've come to the conclusion that most people do, have, or know someone who rides a bike/scooter. As such, everyone can relate to those on two wheels. Expect to see cars pull over and wave you by, as well as motorcycle parking everywhere.
I've only been to Italy once, and I did notice that people on bikes tend to take more risks than in Spain. I think the level of machismo is bit higher in Italy. Germany was also very good, but more people have cars, and I noticed more 'American' style tourist driving in Bavaria.
If you're on any European highway, you'll learn fast to get in the right lane! God I wish they'd enforce that law over hear.