if you have a masters in plant virology can you do PHD in marine biology?

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how close does your masters research have to be to the research you do for your PHD?

If i have a masters in microbiology (plant virology), could i focus on marine biology for my PHD? Or, since my masters research is not related would it be unlikely a prof would take me on as a PHD student in a marine biology lab?
 
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