No doubt! I usually take 2 or 3 and use PHARMACEUTICAL GRADE such as Nordic Naturals. The pharmaceutical grade filters out more than just the mercury. It filters other chemicals. Sometimes the fish oil makes me sick too, so I use organic flax meal. It's ground up fine and you can put it on just about anything. Has about the same effect as far as Omegas go. It WILL lower your cholesterol. ALWAYS read the directions for dosages! I'm a nurse, so that's a must!